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Pinned straw:

Last edited 11 months ago

Clarity Pharmaceuticals has piqued my interest lately. Recently I was diagnosed with prostate cancer and I am a potential beneficiary of this new technology, if the trials are successful and the imaging is approved.

PSMA PET/CT is currently the most accurate imaging test for detecting prostate cancer in men. It has been a game changer as it can detect very small prostate antigen specific cancers that may be missed by other scans and it can more accurately stage cancers.

Clarity Pharmaceutical’s 64Cu SAR-bisPSMA promises another level up in accuracy. In my case the cancer is confined to the prostate… for now! This new technology has the potential to pick up metastatic spread of prostate cancer more accurately and before it becomes a problem.

According to a note shared by James Mickleboro from The Motley Fool, Bell Potter is bullish on the prospects for Clarity in 2025, particularly given the impending release of the final data from the SECuRE trial.

“SECuRE is a Phase I/IIa theranostic trial for identification and treatment of participants with prostate-specific membrane antigen (PSMA)-expressing metastatic castrate-resistant prostate cancer.

Commenting on the company, the broker said:

Clarity Pharmaceuticals has continued to produce high quality interim data readouts from its numerous clinical trials during 2024. In 2025 we anticipate a flood of new data led by headline readouts from the pivotal study in prostate cancer imaging (CLARIFY) and perhaps more importantly, final data from SECuRE being the therapy trial also in prostate cancer.
Earlier data from imaging studies indicates 64Cu SAR-bisPSMA is able to detect cancerous lesions in lymph nodes at a far earlier stage than the standard of care. Similarly, PSA50 data from the SECuRE trial is highly anticipated and is expected to be highly supportive of further development of this drug candidate.

Bell Potter currently has a speculative buy rating and $10.00 price target on its shares.”

Don’t be complacent!

I’d like to take this opportunity to remind all my Strawman mates out there who are over the age of 50 to make sure you have a PSA blood test every year. If you are over 50 and haven’t been tested yet, don’t delay! Make an appointment with your GP today, get a blood test, then rinse and repeat annually. It’s important to establish a trend in PSA results.

I’ve had yearly PSA blood tests for over a decade now. I had no symptoms of prostrate cancer and the rising PSA levels were the only alert I had. This led to follow up testing. An annual PSA blood test can save your life. Don’t be complacent. See the stats below.

I’ve got plenty of mates out there to share my issues with…more than I realised! If you’re one of us and you are struggling to deal with it, or just want to chat about it, feel free to DM me. There is lots of great support out there!

Worldwide, prostate cancer is the second most commonly diagnosed cancer and the fifth leading cause of cancer death among men, with an estimated 1,414,000 new cancer cases and 375,304 deaths in 2020. https://www.prostate.org.au/risk-and-symptoms/facts-figures/#:~:text=Prostate%20cancer%20is%20the%20most,of%20all%20newly%20diagnosed%20cancers.

“Nearly 72 Australian men are diagnosed every day, with 1 in 5 at risk of being diagnosed in their lifetime, according to the estimates. This is because your risk of prostate cancer increases as you get older.

Of the Australian men predicted to be diagnosed with prostate cancer in 2024:

  • 416 (1.8%) will be under 49
  • 3,233 (12.3%) will be 50–59
  • 9,559 (36.3%) will be 60–69
  • 9,584 (36.3%) will be 70–79
  • 3,572 (13.6%) will be over 80


Disc: Not held, but on my watch list

Arizona
Added 11 months ago

@Rick That's rough. I'm sorry to hear you're having that challenge.

I was touched by your post. Your eloquence and matter of factness.

I appreciate your openness

Thanks for the reminder re testing.

All the best to you.

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Rick
Added 11 months ago

Thanks mate! I never thought it would be me!

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Strawman
Added 11 months ago

Sorry to hear that @Rick.

And let me also emphasise the importance of early detection (I ordered a bowel screening test just the other day, but i should also do the PSA with the big 5-0 looming this year..)

fwiw, you're in good company: Buffett was diagnosed with prostate cancer in 2012 and is going strong 13 years later!

Anyway, you got this. Let us know if ever there's anything I can do.

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Rick
Added 11 months ago

Thanks @Strawman. I’m doing OK due to the excellent support I’ve had from some caring mates and generous cancer support organisations. You’re not alone with this!

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Aaronfzr
Added 11 months ago

If I had to pick a cancer to have, Prostate would probably be on the short list. I don't say this at all to make light of your diagnosis but you've got every reason to hope for really excellent outcomes.

But on a long enough time horizon gents, our prostate is coming for all of us.. whether cancer or benign enlargement, its a troublesome little sucker!

Many of us who are males have probably been putting off some health issues for ages - I know I have - so whatever it is, move those meetings and make that GP appointment! A good GP is worth their weight in gold

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mikebrisy
Added 11 months ago

@Rick I echo the thoughts of others here. Thank you for sharing your personal situtation to remind us all about this important topic. Regular GP visits and a PSA test are key to catching this early, so as to have the best possible chances of a good outcome.

I am glad you are getting the support you need - and I am thinking of you and sending positive thoughts! Take care.

(I'm not fully plugged back in to Strawman yet, but was logging on this evening to share some thoughts on $NEU. Still another week mostly on the beach, then some work on my side hustle, before being back in full force for reporting season in a few weeks!)

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GazD
Added 11 months ago

@Rick Sorry to hear this news. I'm, sure you've got it covered but I work with an excellent (IMO) Urologist if you live in Victoria. Just thought I'd ask in mention in case you hadn't settled on a specialist...

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Rick
Added 11 months ago

Thank you all for your kind thoughts and offers of help! The response I’ve received on this thread and by DM has been overwhelming. I’m sure @Strawman never intended this to be a platform for mateship and support…however it has certainly been that for me, and for that I’m very grateful! Thank you all!

…and thanks @GazD. Yes, I have a good Urologist in Toowoomba (Dr Nikhil Sapre) who specialises in robotic surgery.

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edgescape
Added 11 months ago

Sorry to hear that @Rick I am near the age of getting checked

Fwiw I did top up here which is why my holding is suffering but luckily didn't top up in real life after free carrying my holding

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