Pinned straw:
Yes good summary @GazD. The drug and opportunity still seem amazing however it's been horribly managed by Paul Rennie and his team in my opinion.
I'm going to take the David Gardner from Motley Fool approach from here - it's a small part of my portfolio now due to all the dilution, so I'll let it play out and it either goes to zero or becomes a multi bagger over the next couple of years.
That said it was a mistake to buy an unprofitable mid stage biotech and I will not do it again - a hurdle I don't need to jump over. There is just so much that can go wrong and I can't handicap it properly even with some of the early requirements checked off. The only good news is I've only made this mistake once!