Forum Topics OPT OPT #Undervalued

Pinned straw:

Added 10 months ago

New (premium) member

This stock seems "underloved" on Strawman, with only a few posts and only 5 people holding (including me)

I bought in a couple of months ago at around 75 cents

I am not going to post the full investment case. @Aaronfzr has already laid it all out - some good information there.

In short this company basically has one (very) promising drug potentially treating macular degeneration. There was a phase 2 trial around 5 years ago involving over 200 patients, which showed strong statistically-significant improvements when added to current standard-of-case treatment. Phase 3 trials (which will be definitive one way or the other) are due to report soon.

The reason that I am excited about this company is that I believe that there is a fairly high chance of success in the phase 3 trials. The current market cap is $1.25 billion AUD. Even if the trials only show a marginal benefit, or perhaps a benefit in certain subgroups, the company is almost certainly worth multiples of the current price. If there is a large benefit for a majority of patients with macular degeneration, it is possible to end up somewhere near the valuation that @Aaronfzr came up with.

Unfortunately the obvious big risk is that the trials do not show a benefit, in which case the company would be worth very little.

I'm not sure that articulating a precise valuation is useful. However the current price seems to imply a high chance of failure. Even moderately successful results would result in large gains and the best case would end up in the ballpark of $35.

I am not an ophthalmologist, but I do work in medicine and am used to interpreting clinical trial results. For what it is worth, I would personally rate the likelihood of some form of phase 3 success at 50-75%

On that basis, I believe that OPT is clearly undervalued

Aaronfzr
Added 10 months ago

+1 @Goldfish, i strongly agree that $OPT is undervalued based on likely odds of successful trials. To be perfectly frank, based on preliminary data I think it will show an additive - but not amazing - benefit. In that circumstance, the pathway to commercialisation is a little uncertain... it will be bought by (or sell a commercial licence to) one of the entrenched anti-VEG firms to market a combi drug. Unclear how that will look (ok / good / excellent).

But there is a moderate chance it will seriously outperform. Its my largest smallcap holding, and I'd buy more now if it wasn't. Its not quite a binary outcome - it may be worth zero, somewhat more or very much more based on result readouts later this year. (Acknowledging that my view is biased by this conviction.)

Still, on balance of probabilities I agree with @Goldfish this thing is still undervalued (but one of those values is zero). May have burned some long holders but there is definitely light at the end of a tunnel (possibly an oncoming train) ????

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wonkeydonkey
Added 10 months ago

Hey, I hold Opthea IRL I have held it since 2019 and have had a few nibbles at it over the years, the best price I bought it for was 0.58

Its a hard share to love over the years, as it has had its ups and down but maybe there is light at the end of the tunnel


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edgescape
Added 10 months ago

It's not "unloved" when you compare to CMM ;)

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Goldfish
Added 10 months ago

OK I had a quick look at CMM. Probably not for me. Doesn't seem that cheap and the director selling last May that you mention is off-putting

Wish I had bought some 5 years ago at $1 though :-)

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edgescape
Added 10 months ago

CMM was unloved here even at $1! And yes I bought at $1.

I got it here around $2 when I joined before finally selling. Bear77 and me were the only holders that time in Strawman. Not only that CMM had the least votes so I stopped posting and eventually saw that as a sign to sell.

To be honest the directors of CMM deserve to sell after all the hard work they put in.

Anyway the fact that there are holders here in opt already shows there is a following.

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