@Bjbart. An excellent straw. I agree with a multitude of your points….a great person to follow. I also enjoy your insights into other companies we have in common. There are more and more Alzheimer’s drugs coming to market so a well placed product for increasing trials. Eagerly watching the Japanese app media.
@Nerdag please keep doing what you are doing. You are offering a great bear case. This helps everyone to stay on their toes and reassess their bullcase.
Thanks for both of your work.
Cheers
Nnyck777
My opinion but any drug that the entire expert panel refuses to endorse and then members actually resign because of how much they disagree is concerning. Can you find another example of this happening? because it's really that unusual. Then there is the length of time its approved for 9 years which is more than twice as long as its phase 3 trial took. Also a brick wall when you have a drug that doesn't work with a significant side effect profile is unfortunate but to me reeks of sunk cost bias and false hope. Anyway I'm sure its clear I think this was a stupid decision and it lacks transparency.
I just wanted to highlight the existential risk I think it creates where your downside could be sudden and significant even if you view that as unlikely. If this never comes to pass I actually think CGS has a bright future as each study further entrenches it as the standard to which other studies will want to replicate to ensure comparability.