Forum Topics BOT BOT 4C

Pinned straw:

Added a month ago

I’m No Longer Sweating Over This One

Pharmaceutical company $BOT reported their 4C today, having now had their sole anti-Auxiliary Hyper-Hidrosis product on the US market for 11 months.

While I exited $BOT last year after their last 4C at $0.165, my exits are as often poor decisions as my buys, so I attended this morning’s call, and have also poured over the results. I thought it worthwhile writing up, as I observe that there are several long-suffering StrawPeople still holding on, who might therefore presumably be interested in the result and what I think about it.

First to their summary.

 

Their Highlights

• Total prescriptions shipped grew 24% for the quarter from 20,418 in Q1 FY26 to 25,351 in Q2 FY26

• Sofdra net revenue (unaudited) increased from $7.1 million in Q1 FY26 to $9.1 million in Q2 FY26, representing an increase of 28%

• Operating cash outflow increased from $13.1 million in Q1 FY26 to $17.2 million in Q2 FY26, primarily due to the addition of 23 sales professionals and associated one-time start-up costs

• Cash position of $31.5 million on 31 December 2025 and undrawn debt facility of $14.9 million

• New market research showed strong acceptance for Sofdra and SendRx by healthcare professionals, with 90% expecting to increase Sofdra prescribing volume in the next six months

• 50 sales professionals are currently active; new hires and existing sales professionals are highly productive and performing as expected


My Assessment

In a word … underwhelming.


Total Scripts

While total TRx shipped in the quarter was up 24% (that’s a CAGR of +136%), as you can calculate from the graph below, the absolute increase in scripts shipped was +4.9k compared with +6.8k in the prior quarter. This, despite the quarter seeing benefit of the salesforce expansion from the initial 27 Reps, now up to 50 Reps. In fact, this final quarter had the benefit of the expanded workforce for the entire period – albeit, it takes some time for new Reps to get traction with their accounts.

What does this mean? Well, it means that in the 4th quarter in the market we are not in an accelerating growth phase, but at best a linear growth phase, and potentially a declining rate of growth phase. So I am at complete odds with management who use the language “Net Revenue is Accelerating”. I’ll come back to that later.

To give a flavour of how far TRx are falling below the model I updated after Q425, the actual TRx delivered have been 20.4k (Q1) and 25.3k(Q2), whereas my model has 26.6k(Q1) and 42.3k(Q3), so you can see a big gap opening up.

But why, I hear you say, should anyone care what my model says? Well, the reason I care is that it reflects a typical s-curve for a product that reaches peak sales in 3-4 years, shows some of the expected properties of penetrating the prescriber base, and scripts per prescriber and importantly, is the trajectory needed for $BOT to become reasonably profitable in FY27 and not to run out of cash! More on this last point later.

464df85d0d8ef61dad93d200b344a78003e2ff.png

Management said lots of encouraging things on the call in terms of sales force performance, and prescriber intentions. However, prior information about the number of prescribers (from which we can calculated scripts per prescriber per month) have been removed from this report, which is a loss of transparency from my perspective.

(Now, I have to say that it is completely normal for management to not give the level of detail we were provided in the first few reports on an ongoing basis. But they were being given then so that they would establish trends of strong growth, and I believe we’ve now seen the removal of that level of detail because the positive signs have gone. That’s just my hunch, and I have no other reason to base it on.)

Bottom line: last Q I was open to the possibility that we could still be on an accelerating growth trajectory, and that I might have hit the "ejector seat" prematurely. Today’s result confirms my bearish perspective.


Revenue

Net Revenue grew 28% from the last Q, driven both by the increasing TRx and a modest increase in GTN from 23% to 24%. See graph below.

 

72b89b7d9f9ea281293371cc49b8feb21f8e9d.png

As I mentioned before, I don’t like the language of “Net revenue is accelerating”, because the increase in Net Revenue each quarter has followed the sequence: +$3.6m, +$2.8m, +$2.0m despite i) early prescribers gaining experience, ii) coverage of prescribers increasing and iii) the sales force almost doubling over the year.

I fear we will see the revenue growth curve starting to flatten long before the cost base is covered. I think this is the key risk that anyone holding onto this stock needs to assess and satisfy themselves about.

On GTN, management continue to aim to develop GTN to a range of 30-40%. Again, the GTN progression looks to be flattening off, and so I wonder if it can ever make 30%.


Costs

Turning now to costs, I want to examine these in the context of operating cash flows. The chart below, which I’ve pulled from today’s and historical 4C’s needs some explaining.

b36798e60c41d2279b03138b20a59ca7cd4ec6.png

What I like about this picture is that it puts the revenue progression into the context of the relatively large cost base this business has. Any positive trend in OpCF in the last 4 quarters is weak, and there is a significant gap to close.

So with $31m cash remaining, management were asked in the Q&A if they have enough cash to get to cashflow breakeven. The CFO took on the question, and didn’t really answer it. The best I could pull from the rambling response, is that there is enough cash “for the short term”.

To be clear, with a cash burn in the Q of $18m, I’m pretty sure these guys are going to have to raise capital before the end of CY 2026. Why do I say that?

On cash receipts, you can see in the chart the trend (dark dotted line) in what I call “Receipts from Product Sales.” Looks pretty decent, doesn’t.

The problem, is you have to net off the light blue bars, which are essentially the CoPay made to customers (part of the why the GTN is so low).

This means that net receipts from product sales is shown by the light green bar, and the trend over the last 3 Q is shown by the light green dotted line. So, in the context of the operating cost base – the purple bars – this is pretty anaemic operating levage.

If – and it’s a big if – SOFDRA can maintain linear revenue growth for two more years, it is plausible that receipts might cover operating costs. I'm not sure they've got the cash to get there.

I was also bothered about the CFOs remarks about product manufacturing costs. Over the last two quarters, $BOT has had sufficiently inventory in place – not only of finished good, but importantly of the costly API (Active Pharmaceutical Ingredient), so that manufacturing costs have been artificially low. Management made clear that in the Q3 they will have to buy more API, so that will be a increase in cash outflows. But what bothered me was that the CFO then said that in following quarters these costs would return to more normal levels. Wow! As if buying API isn’t a core and ongoing part of manufacturing operations. (I nearly fell off my chair.)

I know I am sounding very negative here. It is possible that with good cost control and continuing increasing sales, that the picture above will evolve and improve significantly with each successive quarter, such that in 12 months’ time we could be looking at a much healthier picture. However, from where we stand today, given that the rate of sales growth may decline into Year 2, and with a relatively high operating cost base locked in, I believe there is a high likelihood that:

1)     Capital will need to be raised in late calendar 2026 or early 2027 and

2)     Profitability will not be achieved until FY27 at earliest, and could be significantly later.


Management Commentary

I’m not going to comment further on what management said, partly because the narrative isn’t really the story that I think the data tells. And frankly, I don’t have any more time to spend on this.

Overall, Vince and Howie seem to be putting a brave face on things, and telling as positive a story as they can without saying anything that is factually misleading. (That is my subjective opinion and impression, rather than something I can factually defend.)


Valuation

According to tradingview.com, analysts have valuations of $BOT with an average TP of $0.775 ($0.24, $2.00, n=4).

I fundamentally disagree. So, what’s my view?

That’s harder to call, and I can't put a number of this one.

As the need for dilution becomes clear, the SP can be expect to fall further. So there is a risk of an unknown level of dilution in the next 1-2 years, and a lot of uncertainty (in my view) as to when a profit might be achieved, if ever. And that’s because, despite impressive q-o-q growth, from my perspective, I can’t see the path to profitability with any confidence.

Why is this? From everything I can tell, $BOT are doing a good job on sales and marketing execution. It's just I am not sure the product is that great, given its cost which is significant. It is also unclear to me what the changes in the Afforable Care Act are going to have on persistency as well as new scripts. Some of the increases in insurance premiums being faced by middle income Americans are pretty scarey, and there are anedoctal reports in the press of people going uninsured. To the uninsured, middle income American, is Sofdra a treatment there are going to pay up for? Interestingly, this was not discussed on the call. Only one question on "impact of tarriffs" ... go figure.

Maybe all of this will change in the next couple of reports. Heaven knows I've been badly wrong on $BOT in that past. But for me, the sidelines is the place to be.

Disc: Not held

Schwerms
Added a month ago

@mikebrisy excellent summary, I wondered if you were still watching this, it's like escaping a car that's gone over a cliff peering over to see if it stayed intact or burst into flames.

It blows my mind the % of net revenue being spend on COGS considering they said no more purchases, thinking back to comments made by management that the cogs should be very small. Net sales of like 6m and cogs excluding API purchases was still like 2mill.

And that Copay expense figure added under net revenue, if they didn't list that separately the revenue would look even worse as shown in your graph.

They can't access the second tranche of the debt because their market cap is too low so no doubt a raise is coming because adding net 2m a quarter gets them nowhere near cashflow positive..

I think the GTN is largely terrible this Q because of the new reps it's like a half repeat of the launch, lots of free units pushed to promote the product which tanks the GTN. That being said the Increase in GTN last Q underwhelmed me.

Only shining light and it's pretty dim is potential seasonality as seen in Japan so it might accelerate a bit end of Q1 / Q2 but I don't see it being anywhere near enough.

I was expecting a worse share price reaction today to be honest but I guess only the faithful remain and not much will shake them.

Disc, not held but still watching with interest whilst licking my wounds.

EDIT: some other comments, might be descending into a rant

interesting to see they don't list as under 2Quarters of funding remaining due to including the debt facility, they can't access the other 14.9m of finance due to market cap to debt ratio. They also have to start paying principal back on the first 30m in April but this can be extended so it is interest only for another 6-12 months.


8d758532edae2aba07f9bd378c877a7609f1a1.png

16e3255752486b3fcba0c4cff4394d738c8a4f.png.


Another point is with the 50 strong team they have only been making a net increase of approx 620 users per month last Q to get that total script amount for the quarter. Fair enough some of them probably only kicked off Oct - Nov

Assuming they will burn another 12-20m next quarter once they resume API purchases but excluding API they did 25300 units for the quarter with a manufacturing cost of $2.7m -- or $100 AUD cost per unit to give net sales after deductions of $276 per unit.

This makes the COGS 36% of the net sales banked.. Excluding API.

They have spent a total over the last 6 Quarters of 34.7m on product manufacturing to ship 62500 units and they need more API? Apparently it costs $100 to assembly a unit given the figures reported last 2 Q exclude API..

So for 62500 units shipped, assembly costs are $6.2m which means they have spent $28.5m on components and somehow need more against net sales of 17m.

The graph in the webinar is misleading as it doesnt include the GTN deduction costs.. 21.m net revenue less 6m in GTN deduction costs, now I can see why they added that line in the last Q so the net revenue looks better, I wondered why we suddenly got to see that.

8ffde4119af655b1d4e8ca25db313cb8d4e9d3.png

Net sales of $276 AUD per unit against forecast GTN of $400 - $450 USD.

The Rise of the AUD back to 70c won't help the cause either.

They will be under 2 Q of cash remaining next quarter unless they leave the inaccessible finance facilities in there, expect a raise of 15-20m between 6 and 8c I am guessing, you never know though.

Rant over think my numbers are mostly correct but can always make mistakes


22

mikebrisy
Added a month ago

@Schwerms "I wondered if you were still watching this, it's like escaping a car that's gone over a cliff peering over to see if it stayed intact or burst into flames."

I think you've summed up precisely the feeling I had. It's not a nice feeling, knowing there are passengers onboard, but the relief to be watching having escaped is palpable.

20

Arizona
Added a month ago

@Schwerms & @mikebrisy I am dusting myself off at the bottom of that cliff, bruised and busted up, having just extracted what I could from the wreckage. I sold out on SM and IRL today. I was wanting for today to see if the thesis was truely broken. Something most Strawpeople worked out months ago. Call me slow.

I got on the call this morning and heard Vinni and Howie talking and it just made me feel like I needed to purge something and fast. I couldn't sit through the whole thing, I have had enough. Those two are a bit too slick for me. I got on board when Matt C was there and in hindsight probably should have called it quits when he left for "Health Reasons".

I'm sure I learnt something after wading into an area of the market I have never waded before. For now just feeling happy to have dragged my sorry arse out of there.

What a ride!!

NOT HELD!!!


20

Schwerms
Added a month ago

@Arizona yes I didn't enjoy my wading in there much either, feel about the same, should have done as @mikebrisy did and sold down when Vince converted those options and sold a bunch in the 40's.

When Matt left was also another reason to reduce exposure but with how they framed it I didnt. He sold down quite a lot once he didn't have to report sales. I haven't rewatched the April interview he did on here but he would have known how poorly it was doing VS expectations during that interview particularly the GTN performance considering all the talk of $400 US or $450 US.

I couldn't attend but hopefully a recording pops up someone on HC usually has a link.

I said licking wounds, feels like licking a few amputations..




18

Schwerms
Added a month ago

Hopefully no more SM passengers on there, only the HC faithful.



15

Arizona
Added a month ago

@Schwerms I remember that interview with Matt. Watching it and feeling like something was off. Shortly after that he stepped down, so I put it down to health issues. But I guess I"ll never know what the story was.

There were a number of points at which I felt management were being a little loose with the truth and lax with the facts. I should have trusted my instincts a lot more with BOT.

Oh well, Onward and Upward!!!

16

Schwerms
Added a month ago

That's it onwards an upwards we go, good to check in every 4C and reinforce the main lessons here..

14

Tom73
Added a month ago

@mikebrisy , thank you for the gentle nudge I needed with your post to sell the remaining half of my BOT position today at the close. I looked briefly at the update this morning and in about 2 minutes it was clear that any hope of things changing soon was not warranted.

In addition to the dwindling cash position and imminent need to raise capital you flag, the GTN was the other catalyst indicated a potential 50% drop from here. The fact they have only got to 24% GTN at the end of the year, which is the high point before GTN get’s smashed in January and February as insurance deductibles reset for the year. A GTN over 20% next quarter would be a miracle! Let’s see how the market reacts to that.

I was also bewildered by the level of spending on inventory. The last capital raise was to cover a large inventory build in anticipation of much much higher sales by this point. They should still be running on much of the previous inventory build. This suggests an even more disturbing assumption, namely that the margins are a lot lower than they expect.

All in all, I reflect on what has been a painful and shocking outcome given the indicators heading into the launch. I still think that the management are as shocked or more shocked than investors at where we are now, this is a separate matter to how they have dealt with and communicated the changing outlook (which is horribly and without transparency), but I can believe that a year ago they thought this was going to be a block buster..

I wonder if we will ever get an honest review of what went wrong from the company? Why given a significantly better go to market model than Japan they couldn’t succeed. What the hell happened to the DTC channel and why has the Dermatologist channel slowed so dramatically from a sprinting start. Maybe it’s just a crap product in the end!

The 2/3 loss from BOT for a large position is a hard pill to swallow, but the beauty of investing is shares can go up a lot more than they can go down, which I am reminded on this day as SGI reached it’s high and over an 11x return for me, which would take more than another 10 BOT’s to take the smile off my face!

23

mikebrisy
Added a month ago

@Tom73 yes, I can see several reasons why there might be a poor Q3:

  • Severe weather keeping people from visiting Derms in Jan, and preventing reps from making visits.
  • Seasonal low GTN, which hits Jan-Mar as you say due to plan deductibles.
  • ACA healthcare premium increases, driving increased copay, lower TRx growth and increased abandonments.


Interestingly, while there appears to be no evidence of seasonality in the seeking of treatment for hyperhidrosis in the US, there is clear evidence from Google Search that online searches involving the keywords realted to hyperhidrosis show a clear summer peak and winter trough for interest in the condition. The picture in Japan is quite different. Here there is clear, peer-reviewed evidence of treatment seasonaity, peaking in late-spring and being lower in the winter.

So there might be a 4th dot point above list, that patient demand is seasonally lower. (For example, with heavier winter clothing (i.e. more absorbant), it is perhaps easier to conceal the condition than in warmer months.)

I'm obviously disappointed with the outcome on $BOT, so far. I was certainly one of the biggest bulls on here, and I put a sizeable position behind it.

However, I was alway open to the risk that the product just might not be that good (to justify its expense). That was always evident in the clinical data. I don't think I allowed the management hype to sway my thinking, although in early last yea when Howie and Matt specifically stated that they felt the market consensus for FY26 looked do-able, I think that was a step too far. I was surprised at the time to hear it, and wondered "what can they see that we can't see". I could only believe that the data from the Patient Experience Program was so strong that they were confident the product was great. But Vince selling down gave me a chill (or rather, made me break out in a sweat), and I am glad I reduced my position when I did at the price that I did, even though it was much lower than my then lofty valuation at the time.

Look, at the end of the day, I am going to continue to take swings in the biotech sector. The majority of them will go through to the keeper. And because of that, when data emerges that erodes my bull case, I'm always going to act swiftly to preserve capital. Capital preservation is a pre-requisite to being able to play another innings!

26

Rocket6
Added 4 weeks ago

@mikebrisy @Tom73 @Arizona @Schwerms well done to you all re: the above. Selling is far more difficult than buying for mine.

Selling out after a stock you have watched for a long time has taken a whack is bloody difficult. The analysis/decision making above will probably result in each of you protecting what will likely be 50% additional capital on the line (at least?)

Continued validation that cheap can always get cheaper.

Note: I am basing this comment on reports that they are raising at 0.6c -- which stands at near 50% dilution. That is, in a word, horrific.

Disc- Not a holder, but I have always kept an eye on BOT. (This is too far outside my area of competence for me to have ever invested)

18

Arizona
Added 4 weeks ago

@Rocket6 It has certainly been a learning experience.

I think I should have known that it was too far outside of my area of competence.

I remember at the beginning, thinking that it was a crazy thing to invest in and decided to keep an open mind, perhaps that is where I went wrong. For a while there it was performing well and I thought "I'm on to something here". Then it was like watching a washing machine fall down a stairwell from the 5th floor. hitting each step with a bone shattering crash. Occasionally it would slow down at a landing teeter for a moment, where I'd breathe a sigh of relief, only to then have it gain momentum, then roll over and start tumbling down the stairs once more.

Note to self: Don't stray from your circle of competence.

22

jcmleng
Added 4 weeks ago

Discl: Not Held

Interesting reading this on the AFR this evening, then going back to @mikebrisy's notes on the Appendix 4C at the top of this thread, where his call was completely right:

"Capital will need to be raised in late calendar 2026 or early 2027"

The significant timing acceleration of this raise and the sharp discount means that things appear to be much more dire than @mikebrisy pointed out ...

-----------------

Street Talk understands fund managers were wall-crossed before midday for a $30 million capital raising and a possible share purchase plan to fund the company’s growth strategy and working capital.

Term sheets later detailed a two-tranche placement with the offer priced at 6¢ – a steep 45.5 per cent discount to the last traded price of 11¢. Botanix Pharmaceuticals was also offering free options to investors on a one-to-one basis, exercisable at 6¢ before January 2027, via joint lead managers Euroz Hartleys and Canaccord Genuity.

The option, exercisable at the heavily discounted offer price, will be highly valuable to incoming investors and further adds to the 45.5 per cent discount. The April 2025 $40 million capital raising was done at a tighter 7 per cent discount.

Fund managers were told the proceeds would be used to purchase pharmaceutical ingredients and manufacturing components, and for advertising and marketing efforts, among other things.


17

Schwerms
Added 3 weeks ago

Big discount because they essentially bullshitted the April raise, really have to incentivise this one

It's probably an ok deal if you have any faith in them but I certainly don't. Mega dilution if all the options end up being exercised

I was calling 30m at 8c but this really trumps my theory.

Maybe it doesn't drop to 6c because this clears up the funding issues

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