@AbelianGrape just a very quick follow up.
https://radiopaedia.org/articles/amyloid-related-imaging-abnormalities-aria
That is a quick link to a pretty decent resource on all things radiographic. I have read the complete NEJM article and whilst it says all of the ARIA -E complicated patients continued with the study it was a little bit more vague on the ARIA-H.
A bit of fluid surrounding your brain is generally less concerning than a bit of blood surrounding your brain that isn’t enclosed within blood vessels.
I think the takeaway on these studies in relation to cogstate is that it’s only going to open a floodgate to further study(s) and some of these will have a very very long follow up. So they are in quite an enviable position.
Everyone knows of someone affected by AZ, so I hope they can make some meaningful progress as it’s truly horrid to watch.